2'-o-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices |
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Authors: | Brennan Lavinia Peng Guomei Srinivasan Natarajan Fox Keith R Brown Tom |
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Affiliation: | School of Chemistry, University of Southampton, Highfield, Southampton, United Kingdom. L.Brennan@soton.ac.uk |
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Abstract: | The nucleoside analogues 2'-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments. |
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