Researches on the etiological agents of the american blastomycosis

Summary and conclusion We have been able to establish typical characteristics of the species, in artificial culture media, of the fungus causingPosadas-Wernicke's disease. Our work is base on the study of ten strains of the fungus and on their retrocultures — obtianed by inoculation of these strains in laboratory animals — in variosu culture media, among them cornmeal agar (Emmons media) which in our opinion is a medium indispensable for the differencing and for the classification of the fungus from other agents which produce syndromes of a like nature.A revision was made of the literature of the morphology of the causal agent ofPosadas-Wernicke's disease and an analysis of the predominant and characteristic fructification of the fungus. In attention to the above facts, we think that the fungus in question should be included in the genusAleurismaLink, 1809. Therefore, admitting the validity of this genus, we believe that the name of the etiological agent ofPosadas-Wernicke's disease should be changed toAleurisma immitis, the diagnosis being justified by the microscopic study inEmmons media and completed by the forms found in a medium rich in glycides. The diagnoses is the following:Aleurisma immitis. — In substratis pauperibus gignuntur hyphis mycelicis hyalinis, septatis, satis ramosis, ramulis in angulo pene recto; aleuriis abundantissimis, valde simplicibus, centralibus et regulariter seriatis, vel apicalibus, rarissime lateralibus, sessilibus, rare pedicellatis, rectangularibus, hyalinis, aliquoties in racemis et thyrsis dispositis. Spirae saepe videntur. In substratis carbohydratis plenis, chlamydosporis intercalaribus et apicalibus abundantibus; aleuriis et spiris nec numerosis aut typicis quam in pauperibus substratis.(so called Coccidioidomycosis)