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Biflavanones, flavonoids, and coumarins from the roots of Stellera chamaejasme and their antiviral effect on hepatitis B virus
Authors:Yang Guohong  Chen Daofeng
Institution:Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 200032, P. R. China.
Abstract:A new 3,3'-biflavanone, isosikokianin A, was isolated from the roots of Stellera chamaejasme, together with eleven known compounds. Their structures and configurations were elucidated by spectroscopic methods including 2D-NMR techniques. Sikokianin A, chamaechromone, and quercetin showed in vitro antiviral activity against HBsAg secretion.
Keywords:Stellera chamaejasme  Isosikokianin A  Biflavanones  Flavonoids  Coumarins  Hepatitis B virus  Antiviral activity
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