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ATP synthase: two motors, two fuels
Authors:Oster G  Wang H
Institution:Departments of Molecular & Cellular Biology, College of Natural Resources, University of California, Berkeley, California 94720-3112, USA. goster@nature.berkeley.edu
Abstract:FoF1 ATPase is the universal protein responsible for ATP synthesis. The enzyme comprises two reversible rotary motors: Fo is either an ion 'turbine' or an ion pump, and F1 is either a hydrolysis motor or an ATP synthesizer. Recent biophysical and biochemical studies have helped to elucidate the operating principles for both motors.
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