| Abstract: | Estimations of plasma total and free testosterone (T) as well as of total and free 17beta-oestradiol (E2) have been performed in 6 normal women throughout the menstrual cycle. The plasma total T levels showed a small but significant cyclical variations, with significantly increased values around the midcycle (p less than 0.001). The pattern of free T during the cycle was similar to total T. Regarding total plasma E2, two typical peaks occurred, which were also observed in plasma free E2. Changes in testosterone-17beta-oestradiol binding globulin have not been detected throughout the menstrual cycle. |
