Ratiometric fluorescence detection of superoxide anion based on AuNPs‐BSA@Tb/GMP nanoscale coordination polymers |
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| Authors: | Nan Liu Juan Hao Keying Cai Mulan Zeng Zhenzhong Huang Lili Chen Bingxian Peng Ping Li Li Wang Yonghai Song |
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| Affiliation: | Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, P. R. China |
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| Abstract: | A novel ratiometric fluorescence nanosensor for superoxide anion (O2??) detection was designed with gold nanoparticles‐bovine serum albumin (AuNPs‐BSA)@terbium/guanosine monophosphate disodium (Tb/GMP) nanoscale coordination polymers (NCPs) (AuNPs‐BSA@Tb/GMP NCPs). The abundant hydroxyl and amino groups of AuNPs‐BSA acted as binding points for the self‐assembly of Tb3+ and GMP to form core‐shell AuNPs‐BSA@Tb/GMP NCP nanosensors. The obtained probe exhibited the characteristic fluorescence emission of both AuNPs‐BSA and Tb/GMP NCPs. The AuNPs‐BSA not only acted as a template to accelerate the growth of Tb/GMP NCPs, but also could be used as the reference fluorescence for the detection of O2??. The resulting AuNPs‐BSA@Tb/GMP NCP ratiometric fluorescence nanosensor for the detection of O2?? demonstrated high sensitivity and selectivity with a wide linear response range (14 nM–10 μM) and a low detection limit (4.7 nM). |
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| Keywords: | AuNPs‐BSA@Tb/GMP fluorescence nanosensor nanoscale coordination polymers ratiometric superoxide anion |
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