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Three-dimensional analysis reveals altered chromatin interaction by enhancer inhibitors harbors TCF7L2-regulated cancer gene signature |
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| Authors: | Diana L. Gerrard Yao Wang Malaina Gaddis Yufan Zhou Junbai Wang Heather Witt Shili Lin Peggy J. Farnham Victor X. Jin Seth E. Frietze |
| Affiliation: | 1. Biomedical Health Sciences Department, University of Vermont, Burlington, VT, USA Cellular, Molecular, and Biomedical Sciences Program, University of Vermont, Burlington, VT, USA;2. Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX, USA;3. Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA;4. Department of Pathology, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway;5. Statistics Department, The Ohio State University, Columbus, OH, USA;6. Biomedical Health Sciences Department, University of Vermont, Burlington, VT, USA |
| Abstract: | |
| Keywords: | altered chromatin interaction chromatin histone acetyltransferase (HAT) tethered chromatin capture (TCC) TCF7L2 pancreatic ductal adenocarcinoma |