Advanced strategies for combating bacterial biofilms |
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Authors: | Javad Yasbolaghi Sharahi Taher Azimi Aref Shariati Hossein Safari Melika Khanzadeh Tehrani Ali Hashemi |
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Affiliation: | 1. Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;2. Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran;3. Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran;4. Health Promotion Research Center, Iran University of Medical Sciences, Tehran, Iran |
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Abstract: | Biofilms are communities of microorganisms that are formed on and attached to living or nonliving surfaces and are surrounded by an extracellular polymeric material. Biofilm formation enjoys several advantages over the pathogens in the colonization process of medical devices and patients' organs. Unlike planktonic cells, biofilms have high intrinsic resistance to antibiotics and sanitizers, and overcoming them is a significant problematic challenge in the medical and food industries. There are no approved treatments to specifically target biofilms. Thus, it is required to study and present innovative and effective methods to combat a bacterial biofilm. In this review, several strategies have been discussed for combating bacterial biofilms to improve healthcare, food safety, and industrial process. |
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Keywords: | antibiofilm molecules bacterial infection biofilm biofilm formation |
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