microRNAs: New prognostic,diagnostic, and therapeutic biomarkers in cervical cancer |
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| Authors: | Javid Sadri Nahand Sima Taghizadeh-boroujeni Mohammad Karimzadeh Sarina Borran Mohammad Hossein Pourhanifeh Mohsen Moghoofei Farah Bokharaei-Salim Sajad Karampoor Amir Jafari Zatollah Asemi Alireza Tbibzadeh Afshin Namdar Hamed Mirzaei |
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| Affiliation: | 1. Department of Virology, Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran;2. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Brujen, Iran;3. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;4. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran;5. Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran;6. Department of Medical Nanotechnology, Faculty of Advanced Technology in Medicine, Iran University of Medical Sciences, Tehran, Iran;7. Department of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada |
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| Abstract: | Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer could be observed in women who infected with papillomavirus, regular oral contraceptives, and multiple pregnancies. Early detection of cervical cancer is one of the most important aspects of the therapy of this malignancy. Despite several efforts, finding and developing new biomarkers for cervical cancer diagnosis are required. Among various prognostic, diagnostic, and therapeutic biomarkers, miRNA have been emerged as powerful biomarkers for detection, treatment, and monitoring of response to therapy in cervical cancer. Here, we summarized various miRNAs as an employable platform for prognostic, diagnostic, and therapeutic biomarkers in the treatment of cervical cancer. |
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| Keywords: | cervical cancer diagnosis exosome Human papillomavirus microRNA therapy |
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