Zhou and He contributed equally to this work.;2. Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China

Zhou and He contributed equally to this work.;3. Laboratory of Department of Surgery, The First Affiliated Hospital of Sun Yat-sen Universitya, Guangzhou, China;4. Division of Vascular Surgery, National-Local Joint Engineering Laboratory of Vascular Disease Treatment, Engineering and Technology Center for Diagnosis and Treatment of Vascular Diseases, Guangdong Engineering Laboratoty of Diagnosis and Treatment of Vascular Disease, The First Affiliated Hospital, Sun Yat-sen University;5. Department of Biomedical Sciences, Department of Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong;6. Center for Molecular and Translational Medicine, Georgia State University, Atlanta, Georgia