Comparison of microRNAs in the intramuscular adipose tissue from Jinhua and Landrace pigs |
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Authors: | Zhiguo Miao Shan Wang Yimin Wang Panpeng Wei Muhammad Akram Khan Jinzhou Zhang Liping Guo Dongyang Liu |
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Institution: | 1. College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang, Henan, China;2. Department of Pathobiology, Faculty of Veterinary and Animal Sciences, PMAS-Arid Agriculture University Rawalpindi, Rawalpindi, Pakistan |
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Abstract: | MicroRNA (miRNA) is critically involved in lipogenesis occurring in various body parts of humans and animals. In this study, to further investigate the role and distribution of miRNA in porcine intramuscular adipose tissue, small RNAs were extracted from Jinhua and Landrace pigs to identify the expression profiles of miRNAs. miRNA expression profiles revealed that 558 miRNAs including 287 known and 271 novel miRNAs were identified, and 220 of them showed differential expression in the pigs. Gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis suggested that the target genes of the differentially expressed miRNAs were involved in fatty metabolism. In conclusion, the current study reveals the active participation of miRNAs in the regulation of adipogenesis in the intramuscular adipose tissue of Jinhua and Landrace pigs. |
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Keywords: | gene expression intramuscular adipose tissue Jinhua pig Landrace pig microRNAs (miRNAs) |
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