Use of stem cells as carriers of oncolytic viruses for cancer treatment |
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| Authors: | Elham Zendedel Stephen L Atkin Amirhossein Sahebkar |
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| Institution: | 1. Department of Biology, Faculty of Sciences, Islamic Azad University-Mashhad Branch, Mashhad, Iran;2. Weill Cornell Medicine Qatar, Doha, Qatar;3. Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran |
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| Abstract: | Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity of stem cells, they can be used as carriers or vectors targeting metastatic cancer. Promising results have been reported regarding the use of stem cells and oncolytic viruses as a therapeutic approach for the treatment of metastatic cancer. The present review aimed to determine the approaches involved in the use of the tumor-homing capacity of stem cells for cancer treatment. |
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| Keywords: | cancer treatment metastatic cancer oncolytic virotherapy stem cell |
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