The effects of fatty acids consumption on OPG/RANKL/RANK system in cardiovascular diseases: Current status and future perspectives for the impact of diet-gene interaction |
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| Authors: | Omid Reza Tamtaji Shokoofeh Borzabadi Majid Ghayour-Mobarhan Gordon Ferns Zatollah Asemi |
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| Institution: | 1. Halal Research Center of IRI, FDA, Tehran, Iran;2. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran;3. Metabolic Syndrome Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;4. Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex, UK;5. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran |
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| Abstract: | Cardiovascular disease (CVD) is an overall term that comprises a number of related pathologies, these include peripheral arterial disease, cerebrovascular disease, coronary heart disease (CHD), venous thromboembolism, and rheumatic and congenital heart diseases. Fatty acids in the diet have been reported to affect CVD. The OPG/RANKL/RANK system appears to have a role in CVD outcomes. However, there have been few studies on the impact of diet-gene interaction for effects of fatty acids consumption on the OPG/RANKL/RANK system in CVD. This review focuses on the effects of fatty acids on OPG/RANKL/RANK in CVD. |
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| Keywords: | cardiovascular disease fatty acids osteoprotegerin |
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