Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart |
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| Authors: | J L Staecker M J Nadakavukaren Dr A Richardson |
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| Institution: | (1) Departments of Chemistry and Biological Sciences, Illinois State University, Normal, Ill, USA;(2) Department of Chemistry, Illinois State University, 61761 Normal, Ill, USA |
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| Abstract: | Summary Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts. |
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| Keywords: | Heart Mitochondria Perfusion Ultrastructure Rat |
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