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大鼠小肠神经激肽A免疫反应(NKA-Ⅰ)物质分布特征的研究
引用本文:李力燕,蔡文琴,王军臣,陈诗芸.大鼠小肠神经激肽A免疫反应(NKA-Ⅰ)物质分布特征的研究[J].中国组织化学与细胞化学杂志,1996(4).
作者姓名:李力燕  蔡文琴  王军臣  陈诗芸
作者单位:昆明医学院,第三军医大学
摘    要:本实验采用免疫细胞化学PAP法,将切片与铺片技术相结合,全面研究了Wistar大鼠(n=20)小肠神经激肽A免疫(NKA-I)阳性物质的分布特征。结果提示:NKA-I神经元单个或多个散在分布于粘膜下和肌间的神经节内,粘膜下神经节处多见。NKA-I神经纤维广泛分布于小肠各段的各层结构中。在小肠粘膜上皮和腺上皮中可见散在分布的NKA-I强阳性细胞,推测为NKA-I内分泌细胞。本文还对NKA-I的形态学特点及生理功能进行了讨论。

关 键 词:大鼠,小肠,神经激肽A,免疫细胞化学

A STUDY OF DISTRIBUTIVE CHARACTERISTICS OF NEUROKININ A IMMUNORENCTIVITY IN SMALL INTESTINE OF RAT
Li Liyan, Cat Wenqin, Wang Jingchen, Chen Shiyen.A STUDY OF DISTRIBUTIVE CHARACTERISTICS OF NEUROKININ A IMMUNORENCTIVITY IN SMALL INTESTINE OF RAT[J].Chinese Journal of Histochemistry and Cytochemistry,1996(4).
Authors:Li Liyan  Cat Wenqin  Wang Jingchen  Chen Shiyen
Abstract:Using PAP immunocytochemistry method (whole mount stretch preparations and cryostat sections), the characteristics of distribution and localization of neurokinin A (NKA) inthe small intestine of rats were studied.The results showed that all layers of small intestine were rich in NKA-immunoreactivity(NKA-I) nerves with a high density in myenteric, submucosal and mucosal plexuses. SomeNKA-I neurons were seen in the myenteric and submucosal plexuese. Besides , there weresome positive NKA-I endocrine cells in the intestinal epithelium and glandular epithelium.The morphological significance and physiological roles of NKA were also discussed.
Keywords:Rat  Small intestine  Neurokinin A  Immunocytochemistry  
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