Two new alliacane sesquiterpenes from the fruiting bodies of edible mushroom Gomphus purpuraceus |
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| Affiliation: | 1. Key Laboratory of Functional Yeast, China National Light Industry & Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, PR China;2. School of Biotechnology and Food Engineering, Changshu Institute of Technology, Suzhou 215500, PR China;3. Three Gorges Public Inspection and Testing Center, Yichang 443005, PR China;4. Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Three Gorges University Medical College, China Three Gorges University, Yichang 443002, PR China;5. Agricultural College, Hubei Three Gorges Polytechnic, Yichang 443000, PR China;1. Hubei Key Laboratory of Natural Products Research and Development, Key Laboratory of Functional Yeast (China National Light Industry), College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, PR China;2. Hubei Hongyu New Packing Materials Co., Ltd., Yichang, PR China;1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, PR China;2. The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, PR China;3. Co-Construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan & Education Ministry of P.R. China, Zhengzhou 450046, PR China;1. School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China;2. Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi’an 710069, China;1. Centre des Sciences du Goût et de l′Alimentation, CNRS, INRAE, Institut Agro, Laboratoire de Pharmacognosie, UFR des Sciences de Santé, Université de Bourgogne Franche-Comté, BP 87900, 21079 Dijon Cedex, France;2. Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan;3. Parasitology and Mycology Laboratory, Hôpital du Bocage, BP 77908, 21079 Dijon Cedex, France;4. PAT Zerbaz, 97410 Saint-Pierre, Ile de la Réunion, France;1. Department of Biological Medicines, School of Pharmacy, Fudan University, Shanghai 201203, PR China;2. Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai 201203, PR China |
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| Abstract: | Two new alliacane sesquiterpenes, named purpuracolide B (1) and purpuracolide C (2), have been isolated from the fruiting bodies of edible mushroom Gomphus purpuraceus. Their structures were elucidated based on spectroscopic studies including electronic circular dichroism calculation. Furthermore, their antiproliferative effects were evaluated in breast cancer cells MCF7, MDA-MB-231 and 4T1. |
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| Keywords: | Alliacane Sesquiterpene Purpuracolide Antiproliferation |
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