Differential expression of the Tmem132 family genes in the developing mouse nervous system |
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| Institution: | 1. Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, PR China;2. Department of Biology, Eberly College of Science and Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA, USA |
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| Abstract: | The family of novel transmembrane proteins (TMEM) 132 have been associated with multiple neurological disorders and cancers in humans, but have hardly been studied in vivo. Here we report the expression patterns of the five Tmem132 genes (a, b, c, d and e) in developing mouse nervous system with RNA in situ hybridization in wholemount embryos and tissue sections. Our results reveal differential and partially overlapping expression of multiple Tmem132 family members in both the central and peripheral nervous system, suggesting potential partial redundancy among them. |
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| Keywords: | Mouse Central nervous system Peripheral nervous system Embryos |
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