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Review on Pregnane Glycosides and Their Biological Activities
Institution:1. Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang 550025, People''s Republic of China;2. The Key Laboratory of Chemistry for Natural Product of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, People''s Republic of China;1. Yunnan Institute of Food Safety, Kunming University of Science and Technology, Kunming 6505000, People''s Republic of China;2. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 6505000, People''s Republic of China;3. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People''s Republic of China
Abstract:Pregnane glycosides are exist in Asclepiadaceae, Apocynaceae, Malpighiaceae, Ranunculaceae and Zygophyllaceae. This is a class of substances with steroids as the mother nucleus and containing a glyosidic bond structure. Modern pharmacology has shown that these compounds are a class of compounds with different structures and multiple biological activities. It has a good development prospect in anti-cancer and anti-tumor directions. This article reviews the chemical structures and biological activities of 345 compounds from 1984 to 2019.
Keywords:pregnane glycosides  biological activities
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