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In vivo and in vitro effects of SREBP-1 on diabetic renal tubular lipid accumulation and RNAi-mediated gene silencing study
Authors:Hao Jun  Zhao Song  Wang Chen  Rong Zanhua  Shi Yonghong  Liu Shuxia  Duan Huijun
Institution:(1) Department of Pathology, Hebei Medical University, No. 361 Zhongshan East Road, Shijiazhuang City, Hebei Province, China
Abstract:
Keywords:SREBP-1 (sterol regulatory element binding protein-1)  FAS (fatty acid synthase)  TGF-β  1 (transforming growth factor-β  1)  Triglyceride  ECM accumulation  Diabetic mellitus  HKC cells (human renal proximal tubular epithelial cells line)  RNA interference
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