BMI and levels of zinc,copper in hair,serum and urine of Turkish male patients with androgenetic alopecia |
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| Institution: | 1. Sutcuimam University, Faculty of Medicine, Department of Dermatology, Kahramanmaras, Turkey;2. Sutcuimam University, Faculty of Medicine, Department of Biochemistry, Kahramanmaras, Turkey;3. Konya Education Research Hospital, Department of Dermatology, Konya, Turkey;4. Fatih University, Faculty of Medicine, Department of Anatomy, Istanbul, Turkey;5. Mersin University, Faculty of Medicine, Department of Biochemistry, Mersin, Turkey;6. Gaziantep University, Faculty of Medicine, Department of Dermatology, Turkey;1. Departamento de Agroindústria, Alimentos e Nutrição da Escola Superior de Agricultura “Luiz de Queiroz”/ ESALQ/USP, Av. Pádua Dias, 11, Caixa postal 9, CEP13418900, Piracicaba/SP, Brazil;2. Faculdade de Nutrição, Laboratório de Nutrição Experimental, Universidade Federal de Alagoas, Campus Universitário A.C Simões, 57072-970, Maceió/ AL, Brazil;3. Laboratório de Nutrição Animal, Centro de Energia Nuclear na Agricultura, CENA/USP, Av. Centenário, 303, Caixa Postal 96, CEP 13416-000, Piracicaba/SP, Brazil;4. Laboratório de Instrumentação Nuclear, Centro de Energia Nuclear na Agricultura, CENA/USP, Av. Centenário, 303, Caixa Postal 96, CEP 13416-000, Piracicaba/SP, Brazil;5. Departamento de Ciências Exatas da Escola Superior de Agricultura “Luiz de Queiroz”/ ESALQ/USP, Av. Centenário, 303, Caixa Postal 96, CEP 13416-000, Piracicaba/SP, Brazil;6. Instituto de Química e Biotecnologia, Laboratório de Pesquisa em Recursos Naturais (LPqRN). Universidade Federal de Alagoas, Campus Universitário A.C Simões, 57072-970, Maceió/ AL, Brazil;1. Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA;2. Hawaii Institute of Marine Biology, University of Hawaii, Kaneohe, HI 96744, USA;1. Department of Rehabilitation Medicine of the Second Hospital Norman Bethune of Jilin University, Changchun 130041, China;2. Institute of Endemic Disease of Jilin University, 1163 Xinmin Street, Changchun 130021, China;3. The First Hospital Norman Bethune of Jilin University, Changchun 130021, China;1. National Institute of Occupational Health, P.O. Box 8149 Dep, N-0033 Oslo, Norway;2. Northwest Public Health Research Centre, 2-Sovetskaya 4, St. Petersburg 191036, Russia;3. Department of Physical and Analytical Chemistry of the University of Oviedo, ES-33006, Spain;4. Department of Medicine, Innlandet Hospital Trust, N-2226 Kongsvinger, Norway;5. North-Western State Medical University, St. Petersburg 191015, Russia;1. University of Minnesota, Minneapolis, Minnesota;2. Department of Dermatology, University of Minnesota, Minneapolis, Minnesota;3. Department of Dermatology, Weill Cornell Medical College, New York, New York |
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| Abstract: | ObjectiveMale pattern androgenetic alopecia is characterized by progressive hair loss from the scalp. It is known that imbalances of some trace elements play a role in the pathomechanism of many forms of alopecia. The aim of this study was to evaluate the levels of zinc and copper in hair, serum and urine samples of Turkish males with male pattern androgenetic alopecia and to compare with healthy controls.Material and methods116 males with male pattern androgenetic alopecia and 100 controls were involved in this study.ResultsLevels of zinc and copper in hair were decreased significantly in the patients (p < 0.05), although zinc and copper levels of serum and urine were not different between patients and controls (p > 0.05). Body mass index of patients were higher than control group. In addition, in the group with body mass index of 25 and lower zinc level in hair and urine, copper level in serum were significantly higher (p < 0.05). Body mass index was negatively correlated with hair zinc levels.ConclusionWe thought that decreased zinc and copper levels in hair may play a role in the etiology of male pattern androgenetic alopecia. In addition, obesity by making changes in the balance of the trace elements in hair, serum and urine may play a role in male pattern androgenetic alopecia. Hence, assessing the levels of trace elements in hair of male pattern androgenetic alopecia patients may be more valuable compared to serum and urine for treatment planning. |
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| Keywords: | Androgenetic alopecia Hair Body fluids Zinc and copper Body mass index |
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