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Iodine nutrition status amongst neonates in Kangra district,Himachal Pradesh
Affiliation:1. Department of Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India;2. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India;1. The Voiland School of Chemical Engineering and Bioengineering, Washington State University, Pullman, WA 99164, USA;2. The Department of Integrated Neuroscience and Physiology, Washington State University, Pullman, WA 99164, USA;1. Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT 05405, United States;2. Department of Chemistry, University of Vermont, Burlington, VT 05405, United States;3. Department of Medicine, University of Vermont, Burlington, VT 05405, United States;1. Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences of the HAS, Magyar tudósok körútja 2, 1117 Budapest, Hungary;2. Institute of Pathophysiology, Semmelweis University, H-1089 Budapest, Hungary;3. Department of Pulmonology, Semmelweis University, H-1125 Budapest, Hungary;4. Laboratory Animal Science Unit, Faculty of Veterinary Science, Szent István University, H-1078 Budapest, Hungary;5. Vetmed Laboratory Ltd., H-1143 Budapest, Hungary;6. Department of Pharmacognosy, Semmelweis University, H-1085 Budapest, Hungary;1. Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060 Krakow, Poland;2. Outpatients Clinic for Drug Prevention and Treatment of Addicts, Św. Katarzyny 3, 31-063 Krakow, Poland;3. Laboratory of Analytical Toxicology and Therapeutic Drug Monitoring, Faculty of Medicine Jagiellonian University, Kopernika 15b, 31-501 Krakow, Poland;4. Laboratory of High Resolution Mass Spectrometry, Regional Laboratory of Physicochemical Analysis and Structural Research, Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060 Krakow, Poland;1. National Institute of Occupational Health, P.O. Box 8149 Dep, N-0033 Oslo, Norway;2. Northwest Public Health Research Centre, 2-Sovetskaya 4, St. Petersburg 191036, Russia;3. Department of Physical and Analytical Chemistry of the University of Oviedo, ES-33006, Spain;4. Department of Medicine, Innlandet Hospital Trust, N-2226 Kongsvinger, Norway;5. North-Western State Medical University, St. Petersburg 191015, Russia
Abstract:Iodine deficiency (ID) is an endemic health problem in Kangra district, Himachal Pradesh (HP) state. ID leads to mental retardation, deaf mutism, squint, dwarfism, spastic diplegia, neurological defects and congenital anomalies. Iodine nutrition status amongst neonates can be assessed by estimating thyroid stimulating hormone (TSH). The present study was conducted with an objective to assess the iodine nutrition status amongst Neonates in Kangra district, HP. All of the hospitals in the district which provide obstetric services were enlisted, of which three were selected for this survey. A total of 613 umbilical cord blood samples of neonates were collected on filter paper and analyzed for TSH. WHO (2007) reported that that a <3% frequency of TSH concentrations above 5 mIU/L in samples collected 3–4 days after birth indicates iodine sufficiency in a population. In our study we found that 73.4% of the neonates had TSH levels of more than 5 mlU/l, thus indicating ID in the population studied. Iodine deficiency continues to be a public health problem in Kangra district, Himachal Pradesh.
Keywords:Iodine  Nutrition  Thyroid stimulating hormone  Neonates  Himachal Pradesh
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