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Mechanisms ensuring optimal conditions of implantation and embryo development in the pig |
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| Authors: | Prza?a Jadwiga Gregoraszczuk Ewa L Kotwica Genowefa Stefańczyk-Krzymowska Stanis?awa Ziecik Adam J Blitek Agnieszka Ptak Anna Rak Anna Wójtowicz Anna Kamiński Tadeusz Siawrys Gabriela Smolińska Nina Franczak Anita Kurowicka Beata Oponowicz Agnieszka Wasowska Barbara Ch?opek Jolanta Kowalczyk Anna E Kaczmarek Monika M Wac?awik Agnieszka |
| Institution: | Department of Animal Physiology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-718 Olsztyn, Poland. jadwigap@uwm.edu.pl |
| Abstract: | The paper summarizes results of a series of studies concerning luteolysis and early pregnancy in pigs. The involvement of the oxytocin (OT)/OT receptor system in the mechanism of corpus luteum (CL) protection during early pregnancy as well as the implication of luteinizing hormone (LH) in the endometrial prostaglandin (PG) release and synthesis are described. In addition, the role of leptin in the regulation of ovarian steroidogenesis and the expression of leptin and its receptor (OB-Rb) genes in hypothalamus, pituitary and reproductive tissues are reported. Moreover, a strong emphasis was placed on the mechanism of PGE2 participation in the local endocrine regulations of reproductive processes occurring in the utero-ovarian area as well as on the vascular endothelial growth factor (VEGF) ligand-receptor system in the ovary and uterus. |
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