Temperature dependent modification of radiosensitivity following hypoxic cytocidal action of chlorpromazine |
| |
Authors: | M. A. Shenoy B. B. Singh |
| |
Affiliation: | 1. Biology & Agriculture Division, Bhabha Atomic Research Center, 400 085, Bombay, India
|
| |
Abstract: | The hypoxic cytotoxic effect of chlorpromazine towards E. coli B/r was observed to be dependent on temperature of incubation and irradiation. Increasing the temperature of incubation from ambient to 37 degrees C followed by irradiation revealed that the organisms showed radiosensitivity of a magnitude which was two to three times the oxygen effect. The possible mechanisms of this effect are discussed. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|