Trends in trace element determinations in blood,serum, and urine of the dutch population,and the role of neutron activation analysis |
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Authors: | Bode Peter de Kok Jaap |
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Institution: | (1) Interfaculty Reactor Institute, Delft University of Technology, Mekelweg 15, 2629 JB Delft, Netherlands;(2) Envirosearch, Sir Winston Churchilllaan 54, 2282JE Rijswijk, Netherlands |
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Abstract: | A critical review on the quality of literature data on trace elements in human blood, serum, and urine of inhabitants in the
Netherlands has shown that many of the currently available data have been established 15–20 years ago. Only in a few publications
are quality indicators mentioned, which should be considered typical—and minimal —for studies resulting at reference values.
The use of neutron activation analysis for determination of trace elements in human body fluids was restricted to a few studies
in the 1970s. However, although it is frequently assumed that the sensitivity of NAA might be insufficient, it is demonstrated
that modern, large, well-type Ge detectors may serve well for the determination of trace elements in human body fluids via
radiochemical NAA, for example. |
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Keywords: | Neutron activation analysis trace elements blood serum urine quality assurance detection limits reference values |
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