The primary structure of a chondrichthyan protamine: A new apparent contradiction in protamine evolution |
| |
| Authors: | Núria Saperas Carlos Buesa Joaquin Abián Jöel Vandekerckhove Harold E Kasinsky Manel Chival |
| |
| Institution: | (1) Departament d'Enginyeria Química, ETSEIB, UPC, Diagonal 647, E-08028 Barcelona, Spain;(2) Flanders Institute of Biotechnology, Department of Biochemistry, Faculty of Medicine, University of Gent, Ledeganchstraat 35, B-9000, Gent, Belgium;(3) Department of Medical Bioanalysis, CID, CSIC, Jordi Girona 18-26, E-08034 Barcelona, Spain;(4) Department of Zoology, University of British Columbia, V6T 1Z4 Vancouver, BC, Canada |
| |
| Abstract: | We have determined the primary structure of protamine R3 from ratfish (Hydrolagus colliei), a species belonging to the order Chimaeriformes (an old phylogenetic line among the chondrichthyes). Protamine R3 contains
48 residues organized as follows: ARRRH SMKKK RKSVR RRKTR KNQRK RKNSL GRSFK (Q/A)HGFL KQPPR FRP. Comparison of this sequence
with both protamine Z3 fromScyliorhinus canicula (a chondrichthyan) and typical protamines from bony fish generates an apparent contradiction: Two relatively close species
(H. colhei andS. canicula, both chondichthyes) display different protamines, whereas species more distant in evolution (S. canicula and bony fish) contain very similar protamine molecules. We note that this is not an isolated case in the evolution of sperm
nuclear basic proteins (SNBPs) and discuss the possible significance of this fact.
Correspondence to: M. Chiva |
| |
| Keywords: | Protamine Primary structure Sperm nucleic basic proteins |
| 本文献已被 SpringerLink 等数据库收录！ |
|
