|
|||||
|
|
Biotransformation of ergot alkaloids by plant cell cultures with high peroxidase activity |
|
| Authors: | M Ščigelová T Macek A Minghetti M Macková P Sedmera V Přikrylová V Křen |
| Institution: | (1) Institute of Microbiology, Academy of Sciences of the Czech Republic, Víde ská 1083, 4 Prague, Czech Republic;(2) Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám stí 2, 6 Prague, Czech Republic;(3) Department of Pharmaceutical Sciences, University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy;(4) Department of Biochemistry and Microbiology, Institute of Chemical Technology, Technická 3, 6 Prague, Czech Republic |
| Abstract: | Ergot alkaloids agroclavine and elymoclavine have been modified using plant cell cultures exhibiting high peroxidase activity. Setoclavine and isosetoclavine have been isolated from media after transformation of agroclavine on a semipreparative scale. 10-Hydroxyelymoclavine resulted from similar treatment of elymoclavine. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |