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Simultaneous improvement of specificity and affinity of aptamers against Streptococcus mutans by in silico maturation for biosensor development |
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| Authors: | Nasa Savory Yayoi Takahashi Kaori Tsukakoshi Hijiri Hasegawa Madoka Takase Koichi Abe Wataru Yoshida Stefano Ferri Shizuko Kumazawa Koji Sode Kazunori Ikebukuro |
| Institution: | 1. Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan;2. Devices Development Center, TDK Corporation, Chiba, Japan;3. +81‐42‐388‐7030+81‐42‐388‐7030 |
| Abstract: | |
| Keywords: | aptamers Streptococcus mutans Cell‐SELEX in silico maturation flow‐through test |