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Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels
Authors:David Tagler  Yogeshwar Makanji  Tao Tu  Beatriz Peñalver Bernabé  Raymond Lee  Jie Zhu  Ekaterina Kniazeva  Jessica E. Hornick  Teresa K. Woodruff  Lonnie D. Shea
Affiliation:1. Department of Chemical and Biological Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois;2. Institute for BioNanotechnology in Medicine (IBNAM), Northwestern University, Chicago, Illinois;3. Feinberg School of Medicine, Northwestern University, Chicago, Illinois;4. Center for Reproductive Science (CRS), Northwestern University, Evanston, Illinois;5. Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois;6. Chemistry of Life Processes Institute (CLP), Northwestern University, Evanston, Illinois;7. +847‐491‐7043+847‐491‐3728
Abstract:
Keywords:tissue engineering  regenerative medicine  ovarian follicle development  primary follicle  ascorbic acid  extracellular matrix  biomaterial  alginate hydrogel
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