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Catalytic synthesis and antioxidant activity of sulfated polysaccharide from Momordica charantia L.
Authors:Xin Liu  Tong Chen  Yan Hu  Kexin Li  Liushui Yan
Affiliation:1. Institute of Integrated Chinese and Western Medicine, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China;2. School of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang, China
Abstract:Sulfated derivatives of polysaccharide from Momordica charantia L. (MCPS) with different degree of sulfation (DS) were synthesized by chlorosulfonic acid method with ionic liquids as solvent. Fourier transform infrared spectra and 13C nuclear magnetic resonance spectra indicated that C‐6 substitution was predominant in MCPS compared with the C‐2 position. Compared with the native polysaccharide from Momordica charantia L. (MCP), MCPS exhibited more excellent antioxidant activities in vitro, which indicated that sulfated modification could enhance antioxidant activities of MCP. Furthermore, high DS and moderate molecular weight could improve the antioxidant activities of polysaccharide. © 2013 Wiley Periodicals, Inc. Biopolymers 101: 210–215, 2014.
Keywords:Momordica charantia L.  sulfated derivatives  polysaccharide  antioxidant
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