A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data |
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| Authors: | Hua Xu Michael A Freitas |
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| Affiliation: | (1) Department of Chemistry, the Ohio State University, Columbus, 43210, OH, USA;(2) Department of Molecular Immunology Virology and Medical Genetics, the Ohio State University, Columbus, 43210, OH, USA |
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| Abstract: | Background Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms have since been developed to automate the process for modern high-throughput LC-MS/MS experiments. |
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