Modelling of drug receptor interaction with birth and death processes |
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| Authors: | H. S. Lam D. G. Lampard |
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| Affiliation: | (1) Department of Electrical Engineering, Monash University, 3168 Clayton, Victoria, Australia |
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| Abstract: | Stochastic modelling of drug receptor interaction at the neuromuscular junction with birth and death processes is presented. Systems with only one drug and two drugs interacting are investigated separately. The total number of receptors is assumed finite and only single receptor binding is considered. It has been possible to obtain exact analytical solutions to forward Kolmogorov equations yielding the transition probability densities and the associated probability generating functions. |
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| Keywords: | Drug receptor interaction Stochastic model Birth and death processes Postsynaptic current noise Muscle relaxants Competition Ionic channel blocking |
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