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Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes |
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| Authors: | Collin Tran Benjamin Heng Jonathan D. Teo Sean J. Humphrey Yanfei Qi Timothy A. Couttas Holly Stefen Merryn Brettle Thomas Fath Gilles J. Guillemin Anthony S. Don |
| Affiliation: | 1. School of Medical Sciences, UNSW Sydney, Kensington, NSW, Australia Centenary Institute, The University of Sydney, Camperdown, NSW, Australia;2. MND Research Centre, Neuroinflammation group, Macquarie University, Sydney, NSW, Australia;3. Centenary Institute, The University of Sydney, Camperdown, NSW, Australia;4. School of Life and Environmental Sciences, The University of Sydney, Camperdown, NSW, Australia;5. Dementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Sciences, Macquarie University, Sydney, NSW, Australia;6. School of Medical Sciences, UNSW Sydney, Kensington, NSW, Australia;7. School of Medical Sciences, UNSW Sydney, Kensington, NSW, Australia Dementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Sciences, Macquarie University, Sydney, NSW, Australia |
| Abstract: | |
| Keywords: | Fingolimod FTY720 LIF neuroprotection S1P sphingosine 1-phosphate |