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A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue plasminogen activator |
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| Authors: | Vincenzo Mattei Valeria Manganelli Stefano Martellucci Antonella Capozzi Elisabetta Mantuano Agostina Longo Alberto Ferri Tina Garofalo Maurizio Sorice Roberta Misasi |
| Affiliation: | 1. Biomedicine and Advanced Technologies Rieti Center, Sabina Universitas, Rieti, Italy;2. Department of Experimental Medicine, Sapienza University, Rome, Italy;3. Department of Experimental Medicine, Sapienza University, Rome, Italy Department of Pathology, University of California at San Diego, La Jolla, CA, USA;4. Institute of Cell Biology and Neurobiology, CNR, Rome, Italy Fondazione Santa Lucia IRCCS, c/o CERC, Rome, Italy |
| Abstract: | |
| Keywords: | GM1 lipid rafts LRP1 methyl-β-cyclodextrin prion protein tPA |