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Tau protein phosphorylation at Thr175 initiates fibril formation via accessibility of the N-terminal phosphatase-activating domain |
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| Authors: | Matthew A. Hintermayer Kathryn Volkening Alexander J. Moszczynski Neil Donison Michael J. Strong |
| Affiliation: | 1. Molecular Brain Research Group, Robarts Research Institute, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada;2. Molecular Brain Research Group, Robarts Research Institute, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada Department of Clinical Neurological Sciences, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada |
| Abstract: | |
| Keywords: | amyotrophic lateral sclerosis chronic traumatic encephalopathy frontotemporal dementia microtubule associated protein tau phosphatase-activating domain |