Na+/H+ exchange in the kidneys of eels (Anguilla anguilla) adapted to sea water or to freshwater environments: Studies with brush border membrane vesicles |
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| Affiliation: | 1. Department of Membrane Transport, Institute of Physiology, Academy of Sciences of the Czech Republic, v.v.i., Videnska 1083, Prague 4, Czech Republic 142 20;2. Drug Resistance Mechanism and Modulation Group, Molecular and Structural Basis of Infectious Systems, National Centre for Scientific Research and Lyon I University Laboratory No. 5086, Institute of Biology and Chemistry of Proteins, Lyon 69 367, France |
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| Abstract: | - 1.1. In brush border membrane vesicles isolated from eel kidneys, adapted either to sea water or freshwater environments, a Na+/H+ antiporter is present.
- 2.2. Using a calibration plot it is possible to evaluate the amount of protons that this antiporter can accumulate inside the vesicular space.
- 3.3. The activity of the antiporter seems to be affected by the salinity of the water; it is higher in animals adapted to seawater.
- 4.4. This adaptation seems to occur by a Jmax regulation of the antiporter.
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