Immunoscintigraphy using different methods of applying a 99mTc labeled monoclonal anti-CEA-antibody in the staging of patients with liver metastases before partial hepatectomy |
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| Institution: | 1. Research & Development Centre, Dubai Electricity and Water Authority (DEWA), P.O. Box 564, Dubai, United Arab Emirates;2. Laboratory of Organic Electronics, Department of Science and Technology, Linköping University, SE-601 74 Norrköping, Sweden;3. Department of Marine Science and Technology, School of Earth and Mineral Sciences, The Federal University of Technology, PMB 704, Akure 340001, Nigeria |
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| Abstract: | It was the aim of this study to determine the value of portal-venous (p.v.), intra-arterial (i.a.) or intravenous (i.v.) IS in the detection of liver metastases. Immediately after angiography and i.a. CT (20 patients) or p.v. CT (6 patients), 0.7–1.2 GBq of the 99mTc labeled anti-CEA MoAb were injected via the i.a. catheter, and in 10 patients i.v. Planar scanning was performed. Using IS in the detection of liver metastases a total sensitivity of 61% was established. However, IS was still found to be the decisive method of excluding extrahepatic tumor deposits. |
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