The positive staining pattern of skin collagen in chronic haemodialysis patients |
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| Institution: | 3. Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, New York, USA;1. Skin Institute, Department of Dermatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan;2. Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, College of Medicine, Tzu Chi University, Hualien, Taiwan;3. Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan |
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| Abstract: | The positive staining pattern of skin collagen fibrils from chronic haemodialysis patients was studied by measn of electron microscopy. Such staining patterns were compared with those from normal control subjects. These visual comparisons reveal that in chronic haemodialysis, fibrils retain normal banding periodicity. Disturbances of collagen molecular or fibril architecture brought about by chronic haemodialysis are also discussed. |
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