An efficient and stereoselective synthesis of beta-D-Arap-(1-->2)-beta-D-Galp-(1-->3)-beta-D-Galp-(1-->4)-alpha-D-Manp, a tetrasaccharide fragment of Leishmania major lipophosphoglycan. |
| |
| Authors: | D V Yashunsky A P Higson A J Ross A V Nikolaev |
| |
| Affiliation: | School of Life Sciences, Division of Biological Chemistry and Molecular Microbiology, Carnelley Building, University of Dundee, Dundee DD1 4HN, UK. |
| |
| Abstract: | A tetrasaccharide fragment of Leishmania major lipophosphoglycan (which seems to be involved in a biological mechanism for the parasite transmission) has been synthesised using the thioglycoside, trichloroacetimidate and halide-exchange glycosylation procedures and step-wise chain elongation strategy. |
| |
| Keywords: | |
|
|
