Equol an isoflavonoid: potential for improved prostate health, <Emphasis Type="Italic">in vitro</Emphasis> and <Emphasis Type="Italic">in vivo</Emphasis>evidence |
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| Authors: | Trent D Lund Crystal Blake Lihong Bu Amy N Hamaker Edwin D Lephart |
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| Institution: | (1) Stoelting Co, 60191 Wood Dale, IL, USA;(2) The Department of Physiology and Developmental Biology and the Neuroscience Center, Brigham Young University, 84602 Provo, Utah, USA;(3) MRDDRC Imaging Core, Department of Neurobiology, Children’s Hospital Boston and Harvard Medical School, 02115 Boston, MA, USA |
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| Abstract: | Background To determine: in vitro binding affinity of equol for 5alpha-dihydrotestosterone (5alpha-DHT), in vitro effects of equol treatment in human prostate cancer (LNCap) cells, and in vivo effects of equol on rat prostate weight and circulating levels of sex steroid hormones. |
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