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Paecilotoxin production in clinical or terrestrial isolates of Paecilomyces lilacinus strains |
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| Authors: | Yuzuru Mikami Katsukiyo Yazawa Kazutaka Fukushima Tadashi Arai Shun-ichi Udagawa Robert A Samson |
| Institution: | (1) Department of Experimental Chemotherapy, Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1, Inohana, 280 Chiba, Japan;(2) Division of Microbiology, National Institute of Hygienic Sciences, 1-18-1, Kamiyoga, Setagaya-ku, 158 Tokyo, Japan;(3) Centraalbureau voor Schimmelcultures, 3740 AG Baarn, The Netherlands |
| Abstract: | The production of paecilotoxin from various isolates of Paecilomyces lilacinus was studied using three different media and high performance liquid chromatography (HPLC). Alkaline medium was found to be suitable for the production of the toxins. Among 20 strains tested, 19 including four clinical isolates were found to produce the toxins. Production patterns of paecilotoxins were very similar in each strain and the main toxins were A and B. |
| Keywords: | Paecilomyces lilacinus paecilotoxin distribution HPLC clinical isolates entomopathogenic nematode-killing fungi |
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