Molecular-biological characteristics of rubella virus strains isolated in St. Petersburg |
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| Authors: | Zh V Buzitskaya A K Sirotkin T M Gudkova A R Prochukhanova A V Karpov L M Tsybalova O I Kiselev |
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| Institution: | (1) Department of Ophthalmology, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan;(2) Department of Virology III, National Institute of Infectious Disease, 4-7-1 Gakuen, Musashi Murayama-shi, Tokyo 208-0011, Japan |
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| Abstract: | In the surveillance of the incidence of rubella in the northwestern region of Russia, an analysis was conducted of swabs from the noses and pharynxes of 37 patients with rubella treated in Solovev District Military Clinical Hospital No. 442. To isolate the virus, the RK-13 cell line was used, in total 22 strains were allocated. The strains of the Rubella virus isolated in St. Petersburg during the 2007 outbreak belong to the 1E genotype. In the culture of RK-13 cells, changes of cellular morphogenesis and the formation of replicative complexes, as well as the shells of virions of rubella viruses, were detected. |
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