Taenia solium cysticercosis: An under-recognized but serious publica health problem |
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| Affiliation: | 1. State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, PR China;2. Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing 211800, PR China;1. School of Mathematics and Statistics, Nanjing University of Information Science and Technology, Nanjing 210044, China;2. School of Mathematics, Southeast University, Nanjing 210096, China;1. Department of Neurophysiology, Juntendo University School of Medicine, Tokyo, Japan;2. Department of Radiology, Juntendo University School of Medicine, Tokyo, Japan;3. Research Institute for Diseases of Old Age, Juntendo University School of Medicine, Tokyo, Japan;4. Sportology Center, Juntendo University School of Medicine, Tokyo, Japan;5. Advanced Research Institute for Health Science, Juntendo University School of Medicine, Tokyo, Japan |
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| Abstract: | The true impact and scope of the disease cysticercosis have been obscured by the lack of sensitive and specific diagnostic tools for the collection of reliable epidemiological data. Diagnosis has hitherto been dependent on clinical observations, radiologic imaging, and serologic assays that employ crude, non-specific antigens. These methods suffer from high cost and inaccessibility, and lack reliability. Development of the cysticercosis-specific glycoprotein antigens and their use in immunoblot have given us a diagnostic tool with high sensitivity and exquisite specificity. As discussed here by Victor Tsang and Marianna Wilson, use of this assay in recent epidemiologic studies has demonstrated the serious impact of cysticercosis to public health and the economy of the pork industry. |
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