Peri-rolandic and fronto-parietal components of scalp-recorded giant SEPs in cortical myoclonus |
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| Affiliation: | 1. Department of Brain Pathophysiology, Kyoto Uniuersity School of Medicine, Shogoin, Sakyo-ku, Kyoto 606, Japan;2. Department of Neurology, Kyoto Uniuersity School of Medicine, Shogoin, Sakyo-ku, Kyoto 606, Japan;3. Kansai Epilepsy Center, National Utano Hospital, Kyoto, Japan;4. Department of Neurology, Kyoto Municipal Hospital, Kyoto, Japan;1. Department of Pediatric Neurosurgery, Tel Aviv-Sourasky Medical Center, Tel Aviv, Israel;2. Division of Pediatric Neurosurgery, NYU Langone Medical Center, New York, New York, USA;3. Pediatric Neurosurgery, Washington University School of Medicine, St. Louis Children''s Hospital, St. Louis, Missouri, USA;4. Pediatric Neurosurgery, Charité Universitaetsmedizin, Berlin, Germany;5. Division of Pediatric Neurosurgery, Santobono-Pausilipon Children''s Hospital, Naples, Italy;6. Department of Woman, Child, General and Specialistic Surgery - “Luigi Vanvitelli“ Campania University, Naples, Italy;1. Department of Primary Health Care and General Practice, University of Otago-Wellington, New Zealand;2. Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland;3. Dalhousie University, Canada;4. Director Immunisation Advisory Centre, University of Auckland, New Zealand |
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| Abstract: | Scalp topography of giant SEPs to median nerve stimulation was studied in 4 patients with cortical myoclonus of various etiology. The positive peak (P30) at the contralateral parietal area was simultaneously accompanied by a negative peak at the frontal area (N30), and at least one of these two peaks was enhanced in 2 patients. Another positive peak (P25) and a negative peak (N35) were also identified at the peri-rolandic area with different latency from P30 and N30, respectively, in all patients. N35 was enhanced in 3 patients, and P25 in 2 patients. It is concluded that, as seen in normal subjects, tangential (P30-N30) and radial (P25 and N35) components of SEPs are most likely distinguishable in giant SEPs, and that either one or both of those components is enhanced in different ways depending on the patients. |
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