Susceptibility of Candida albicans from Cystic Fibrosis Patients |
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| Authors: | Raquel Sabino Elisabete Carolino Richard B. Moss Niaz Banaei Cristina Verissimo David A. Stevens |
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| Affiliation: | 1.Infectious Diseases Department,National Institute of Health Dr. Ricardo Jorge, URSZ,Lisbon,Portugal;2.Scientific Area of Mathematics,Lisbon School of Health Technology, Polytechnic Institute of Lisbon,Lisbon,Portugal;3.Division of Pulmonology, Department of Pediatrics,Stanford School of Medicine, Stanford University,Stanford,USA;4.Department of Pathology,Stanford School of Medicine, Stanford University,Stanford,USA;5.Division of Infectious Disease and Geographic Medicine, Department of Medicine,Stanford School of Medicine, Stanford University,Stanford,USA;6.California Institute for Medical Research,San Jose,USA |
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| Abstract: | Candida albicans is a common microbe, colonizer and potential pathogen found in respiratory cultures of cystic fibrosis (CF) patients. Because of possible development of resistance in patient isolates resulting from residence in the abnormal milieu of CF patient airways, or from exposure to antifungals, and considering the possibility of patient-to-patient spread of microbes and reports of elevated resistance to other fungal pathogens, it was important to assay the susceptibility of isolates of Candida and compare that profile to isolates from the community. In our center, and unlike another fungal pathogen, no increase in resistance of Candida isolates of the CF cohort was found. |
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