A novel 1,8-naphthalimide-based fluorescent chemosensor for the detection of HSA in living cells |
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| Authors: | Liuting Mo Wanqi He Yonghe Tang Danlian Liang Chan Yang Weiying Lin |
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| Institution: | Guangxi Key Laboratory of Electrochemical Energy Materials, Institute of Optical Materials and Chemical Biology, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi, China |
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| Abstract: | Human serum albumin (HSA) is an essential protein for maintaining human health. Accurate detection and quantification of HSA are of great significance for disease diagnosis and biochemical research. Here, a new HSA fluorescent probe BNPE based on the 1,8-naphthalimide fluorophore was designed and synthesized. The probe could recognize HSA through a twisted intramolecular charge transfer mechanism, effectively avoid the interference of most substances, and realize HSA fluorescence imaging in living cells. |
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| Keywords: | fluorescent probe HSA live-cell imaging protein detection |
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