Structurally Diverse Sesquiterpenoids from the Genus of Ainsliaea |
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| Authors: | Yi-Xin Zhuang Shu-Xuan Wang Shan-Rong Luo Lie-Feng Ma Zha-Jun Zhan |
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| Affiliation: | 1. Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China These authors contributed equally to this work.;2. Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China |
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| Abstract: | The genus of Ainsliaea embraces approximately 70 recognized species, many of which have been used to treat various diseases in folklore medicines. As the main metabolites of Ainsliaea plants, Ainsliaea sesquiterpenoids have drawn considerable attention in related scientific communities due to their intriguing structures and a variety of bioactivities. In this review, we intend to provide a full-aspect coverage of sesquiterpenoids reported from the genus of Ainsliaea, including 145 monomeric sesquiterpenoids and 30 oligomeric ones. Multiple aspects will be summarized, including their classification, distributions, structures, bioactivities, and biomimetic syntheses. In addition, their possible biosynthetic pathway will be discussed in detail. |
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| Keywords: | Ainsliaea biological activities dimeric sesquiterpenoids oligomeric sesquiterpenoid sesquiterpenoid |
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