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Extraction of Functional Compounds from Tarragon (Artemisia dracunculus L.) by Deep Eutectic Solvents at Different Properties
Authors:Dr. Yusuf Can Gerçek  Assoc. Prof. Dr. Naciye Kutlu  Saffet Çelik  Dr. Betül Gıdık  Sinan Bayram  Assoc. Prof. Dr. Nesrin Ecem Bayram
Affiliation:1. Department of Biology, Faculty of Science, Istanbul University, 34116 Istanbul, Turkey

Center for Plant and Herbal Products Research-Development, 34134 Istanbul, Turkey;2. Department of Food Processing, Aydıntepe Vocational College, Bayburt University, 69500 Bayburt, Turkey;3. Technology Research and Development Application and Research Center, Trakya University, 22100 Edirne, Turkey;4. Department of Organic Farming Management, Faculty of Applied Science, Bayburt University, 69000 Bayburt, Turkey;5. Department of Medical Services and Techniques, Vocational School of Health Services, Bayburt University, 69000 Bayburt, Turkey

Abstract:In this study, it was aimed to examine the capacity of deep eutectic solvents (DESs) with different contents to extract bioactive compounds from tarragon (Artemisia dracunculus L.) plant. For this reason, the total phenolic-flavonoid content, total proanthocyanidin content and antioxidant/antimicrobial activities of the prepared DES extracts were investigated, as well as the individual phenolic and individual amino acid profiles. According to the results, DES10 had the highest efficiency in terms of its capacity to extract individual phenolics (approximately 59 mg/100 g) and individual amino acids (approximately 2500 mg/kg), and also gave a higher yield compared to ethanol (approximately 44 mg/100 g for individual phenolics and about 19810 mg/kg for individual amino acids) and methanol (approximately 58 mg/100 g for individual phenolics and approximately 21430 mg/kg for individual amino acids). However, the total phenolic content, total flavonoid content and antioxidant activity values of DES extracts were determined between 59.09–77.50 mg GAE/100 g, 28.68–45.55 mg GAE/100 g and 42.96–146.86 mg TE/100 g, respectively. Therefore, it can be recommended to use these green solvents, which are known as environmentally friendly, as an alternative to organic solvents in the process of preparing extracts of this important medicinal plant in different areas.
Keywords:Tarragon  deep eutectic solvents  extraction  bioactive compound  antimicrobial activity
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