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Quantitation of deoxycorticosterone and its relationship to progesterone in the prepartum bovine.
Authors:T H Wise  A M Sorensen  J L Fleeger
Institution:Physiology of Reproduction, Department of Animal Science, Texas Agricultural Experiment Station, College Station, Texas 77843 USA
Abstract:A method and its validation is described for the radioimmunological measurement of deoxycorticosterone (DOC) in bovine serum. Levels of DOC and progesterone were determined in six pregnant heifers from one to three weeks before and during parturition. Levels of these steroids fluctuated widely from day to day and tended to be inversely related (r = -0.24). High levels of DOC in conjunction with low levels of progesterone at or near parturition are suggestive that DOC is involved in the parturition process.
Keywords:Progesterone (P)  4-pregnene-3  20-dione  Deoxycorticosterone (DOC)  21-hydroxy-4-pregnene-3  20-dione  Deoxycorticosterone acetate (DOCA)  21-hydroxy-4-pregnene-3  20-dione acetate  17-hydroxyprogesterone (17-OHP)  17-hydroxy-4-pregnene-3  20-dione  5α-17-hydroxyprogesterone (5α-17-OHP)  17-hydroxy-5α-pregnane-3  20-dione
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