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Sampling of sentinel lymph nodes: a simulation study
Authors:Celasun Bülent  Mumcuoğlu Erkan U  Kalkan Habil
Institution:Department of Pathology, Ba?kent University School of Medicine, Bah?elievler, 06490 Ankara, Turkey. bulent.celasun@superonline.com
Abstract:OBJECTIVE: To analyze the effects of various slicing schemes on the detection of metastases in lymph nodes. STUDY DESIGN: Use of an advanced computer simulation tool. RESULTS: Bisectioning along the longitudinal axis is an inadequate approach. Slicing ellipsoid lymph nodes along their longitudinal axis also results in a lower rate of detecting metastases since metastatic deposits have a predilection to localize subcapsularly. CONCLUSION: Ellipsoid lymph nodes must be sliced perpendicular to the longest axis to increase the rate of detecting metastases.
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