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Extra-skeletal multiple myeloma presenting with an atrial mass: a case report and a review of the literature
Authors:Federica Vigo  Patrizia Ciammella  Riccardo Valli  Elisabetta Cagni  Cinzia Iotti
Abstract:ABSTRACT: INTRODUCTION: Extraskeletal presentation at diagnosis or during the course of multiple myeloma is a rareevent. The prognosis is usually very poor. At the moment there is no agreed gold standard forthe treatment of this presentation. CASE PRESENTATION: A 79-year-old Caucasian woman was treated at our hospital for right atrial myelomalocalization. Our patient showed the following signs and symptoms of congestive heartfailure: dyspnea, hypotension, cyanosis and facial edema. Surgery was not consideredfeasible due to the extent of the disease. Our patient underwent external-beam radiationtherapy using an intensity modulated technique, thus obtaining a persistent completeremission. Our patient has been in continuous complete local remission for 25 months sincethe end of radiotherapy. CONCLUSION: The role of radiotherapy is not defined in multiple myeloma with extraskeletal presentation.Our regimen seems to be effective in controlling the disease in this patient.This case report adds to the existing literature as it describes an unusual presentation of thedisease and a new therapeutic approach to this rare presentation of multiple myeloma.
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